molecular genomics


ecosystem impacts


global change


mutations 2 global change (m2gc)


This is a journal club / seminar series based at Carnegie & Stanford.

We aim to bring together molecular biologists, evolutionary geneticists, epidemiologists, ecologists, and climate scientists, and analyze frontier research to anticipate biological changes that can affect human or ecosystem health in a changing world, and brainstorm about potential solutions.


> Meeting variably every second week. To be up-to-date with rooms and times, check this web, access our m2gc calendar or join the googlegroup by sending a blank email to mutations2globalchange+subscribe@googlegroups.com .

> Moi Exposito-Alonso (moisesexpositoalonso@gmail.com)

SCHEDULE (updated as speakers/papers are confirmed)

Future speakers TBC: Rachael Bay (UC Davis)


  • Jan 16, 2019 (11am Carnegie Seminar room) Grey Monroe (Max Planck Institute and UC Davis), will tell us about his work on Loss of Function mutations in Arabidopsis and their relevance to climate adaptation (http://dx.doi.org/10.7554/eLife.41038)
  • Dec 12 2019 (together with Pritchard Lab Journal Club) we will discuss (via Skype) with Laura Hayward her recent theory paper on polygenic adaptation after a sudden change in the environment (dx.doi.org/10.1101/792952).
  • Dec 5 2019 (13:30 Carnegie Seminar room) will feature a talk by Matthew Kling (UC Berkeley) on (http://matthewkling.github.io/media/).
  • Nov 26 2019 (9am Global Ecology conference room) will feature a videoconference talk from Tom Crowther (ETH) and we will discuss the recent global restoration projection paper (dx.doi.org/10.1126/science.aax0848), which recently proposed 0.9 billion hectares of canopy cover could be restored to sink 205 gigatonnes of CO2.
  • Nov 21 (11am Carnegie Seminar room) will feature a talk by Valentino Gantz (UC San Diego) on his co-invention, CRISPR gene drives (doi.org/10.1073/pnas.1521077112), to "control" species demographic and evolutionary fates.
  • [ Two weeks where we will join two CEHG.stanford.edu talks, one by Moi (Oct 30 12pm MSOB X303) on the latest paper of genomic predictions under climate change (dx.doi.org/10.1038/s41586-019-1520-9), and another from Chris Kyriazis (UCLA) (Nov 6 12pm Clark S360) in unintended maladaptation consequences of genetic restoration of threatened populations (dx.doi.org/10.1101/678524) ]
  • Oct 24 2019 (9am Carnegie Global Ecology conference room) will feature a videoconference talk by Richard Neher (Basel Biozentrum) and we will discuss his nextrain.org platform (dx.doi.org/10.1093/bioinformatics/bty407). This is a virus evolution monitoring website feeding from global clinical datasets that uses phylogenetics to predict the next infectious strains.
  • Oct 17 2019 (1.30pm Carnegie Library room) we will have a videoconference with Ruth Shaw (U Minnesota) and discuss her paper (doi.org/10.1086/700565) on the limits of evolutionary prediction. This paper is also a great introduction to a century of mathematical population genetics.